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| Billy Crystal | Harry Burns | |
| Meg Ryan | Sally Albright | |
| Carrie Fisher | Marie | |
| Bruce Kirby Jr. | Jess | |
| Steven Ford | Joe | |
| Lisa Jane Persky | Alice | |
| Michelle Nicastro | Amanda | |
| Gretchen Palmer | Stewardess | |
| Robert Alan Beuth | Man on Aisle | |
| David Burdick | 9 Year Old Boy | |
| Joe Viviani | Judge | |
| Harley Jane Kozak | Helen | |
| Joseph Hunt | Waiter at Wedding | |
| Kevin Rooney | Ira | |
| Franc Luz | Julian | |
| Tracy Reiner | Emily | |
| Kyle T. Heffner | Gary | |
| Kimberley LaMarque | Waitress | |
| Stacey Katzin | Hostess | |
| Estelle Reiner | Older Woman Customer | 
| Director | 
              
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| Producer | Rob Reiner
               Nora Ephron Andrew Scheinman Steve Nicolaides  | 
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| Writer | Nora Ephron
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| Cinematography | 
              Barry Sonnenfeld
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             During their travel from Chicago to New York, Harry and Sally debate whether or not sex ruins a friendship between a man and a woman. Eleven years later, and they're still no closer to finding the answer.  | 
        
            
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